Health Monitor: Care for your Gut  |  Education Information: CBSE cancels class 10 Board Exams, postpones Class 12th Board Exams  |  Policy Indications: Dr Harsh Vardhan announces launch of `Aahaar Kranti’  |  Teacher Insights: X or Y? Learning is Beyond Getting the Equations Right!  |  Policy Indications: Atal Innovation Mission collaborates with Bayer  |  Parent Interventions: NITI Aayog Launches‘Poshan Gyan’, a Digital Repository on Nutrition Information  |  Education Information: EdCIL pays a highest ever dividend of Rs 12.5 Crore for the year 2019-20  |  National Edu News: Fitness Challenge for the Nation - 70th RRT Conference Intl. on 16th April  |  Parent Interventions: Reading for Fun Improves Language Skills  |  Technology Inceptions: Xiaomi Redmi Note 10 Pro  |  Technology Inceptions: Canon New image Runner Advance Dx  |  Technology Inceptions: Boat Bar 4000 DA  |  Teacher Insights: Digital Tool to Detect Fake News  |  Science Innovations: HGCO19: starting the enrolment for the PhaseI/II human clinical trials  |  National Edu News: Scientists discover the farthest Gamma-ray emitting active galaxy   |  
January 06, 2021 Wednesday 11:55:51 AM IST

Synthetic Probe for Visualising Chromosome

Science Innovations

Kyoto University scientists have developed a new synthetic probe that offers a safe and straightforward approach for visualising chromosome tips in living cells. This could advance research into aging and a wide range of diseases, including cancers. Telomeres protect chromosome ends that are constantly at risk of degradation and fusion. Telomeres are made of long repeating DNA sequences and bound proteins. Malfunction of telomeres causes cancer. Telomeres normally shorten with each cell division until they reach their limit, causing cell death. Visualising telomeres, especially their physical arrangements in real-time, is important for understanding their relevance to disease and aging. The new synthetic pyrrole-imidazole polyamide (PIP) probe precisely delivers a fluorescent compound to telomeres on the tips of chromosomes.