National Edu News: Specialised Training Required for Implementing ECCE: Dr Venita Kaul  |  Cover Story: Elimination Round or Aptitude Test- How to Align CUET with NEP 2020 Goals  |  Life Inspirations: Master of a Dog House  |  Education Information: Climate Predictions: Is it all a Piffle!  |  Leadership Instincts: Raj Mashruwala Establishes CfHE Vagbhata Chair in Medical Devices at IITH   |  Parent Interventions: What Books Children Must Read this Summer Vacation   |  Rajagiri Round Table: Is Time Ripe for Entrepreneurial Universities in India?  |  Life Inspirations: How to Overcome Fear of Public Speaking  |  Teacher Insights: Guided Play Effective for Children  |  Teacher Insights: Doing Calculations Boosts Mental Strength  |  Best Practices: Hugging for Happiness  |  Parent Interventions: Is Frequent Childcare Outside of the Family Beneficial for a Child's Development  |  Health Monitor: How to Measure Attention?  |  Life Inspirations: From BC to AC: What Has Changed in Pandemic and What Has Not  |  Guest Column: The Biting Army  |  
February 24, 2020 Monday 03:55:57 PM IST

Natural sugars in breastmilk may influence child's growth

Parent Interventions

Human milk oligosaccharides (HMOs) found in breastmilk may influence a child's growth from infancy through early childhood, according to a study supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH). The study also suggested that maternal obesity may affect HMO composition in breastmilk. The study was led by Lars Bode, Ph.D., at the University of California, San Diego. It appears in The American Journal of Clinical Nutrition.

HMOs are complex sugars found in breastmilk, but infants do not digest them directly. Instead, HMOs serve as prebiotics by influencing the composition of the gut microbiome. Previous studies have found that HMOs may also protect infants from disease-causing microbes. Approximately 150 types of HMOs are known, and mothers have unique combinations and concentrations of them in their breastmilk, influenced in part by genetics and the types of HMO-processing enzymes they have. 

Researchers evaluated approximately 800 pairs of mothers and children in a Finnish study of child development. The researchers analyzed the content of HMOs in breastmilk samples (collected when the children were 3 months old), among them two HMOs that are now added to some commercial infant formulas: 2'-fucosyllactose (2'FL) and lacto-N-neo-tetraose (LNnT). 

Breastmilk from mothers of taller and heavier infants and children tended to have less diverse HMO composition, higher concentrations of 2'FL and lower concentrations of LNnT. Breastmilk from overweight and obese mothers also tended to have less diverse HMO composition, higher concentrations of 2'FL and lower concentrations of LNnT.


According to the authors, these results confirm the findings of two of their previous smaller studies. Together, the three studies found similar patterns of HMO composition and child growth among three different groups of mothers. The authors noted that, although their study linked HMO composition with early childhood growth, it couldn't prove that variations in HMO patterns cause differences in children's growth. If additional studies confirm their findings, specific HMOs might one day provide treatment for early childhood growth problems and obesity. 


(Content Courtesy: https://www.eurekalert.org/pub_releases/2020-02/nksn-nsl021420.php)



Comments