Teacher Insights: How Digital Technology Helps in Growth and Access to Quality Education  |  Management lessons: How Brands Use CARE to Stay on Top in Instagram  |  Hobbies &Trends: At Full Throttle  |  Finance: Bitcoin Mobile Apps Vulnerable to Security Threats: Guan-Hua Tu, MSU  |  International Edu News: Use plants' ability to tell the time to make food production more sustainable  |  International Edu News: Scientists develop new class of cancer drug with potential to treat leukaemia  |  International Edu News: Loan applications processed around midday more likely to be rejected  |  International Edu News: Researchers find climate change impacts plankton – a key marine food source  |  International Edu News: Nature must be a partner, not just a provider of services – Oxford report  |  National Edu News: Approval to MoU between India and UK on Global Innovation Partnership  |  National Edu News: Transfer of CSIR-CMERI technologies to three MSMEs  |  Parent Interventions: Child Learning Programs: How to Find the Right One for You  |  Rajagiri Round Table: Fitness Challenge for the Nation  |  Education Information: West Bengal Scholarship 2021  |  Education Information: What is PMEGP Scheme? How can you get it?  |  
May 28, 2020 Thursday 01:14:05 PM IST

Micro Deletion Syndrome Leads to Schizophrenia

image by mohamed hassan for pixabay

Individuals with 22q11.2 micro deletion syndrome- a rare genetic disorder will develop schizophrenia together with one of its most common symptoms, auditory hallucinations, according to a study done by University of Geneva Faculty of Medicine. Stephen Eliez, a Professor in Department of Psychiatry said that patients with 22q11.2 micro deletion syndrome, a rare neurogenetic syndrome are prone to auditory hallucinations. More importantly 30 to 35% of them develop schizophrenia during their life time This is the category with the highest risk of falling victim to the psychotic disorder. 
About 230 people from Switzerland, France, Belgium, Luxemburg and England in the 8 to 35 age group were assesed “We discovered that the thalamic nuclei involved in auditory and vi-sual sensory processing and working memory are smaller in people with deletion syndrome than in others, explains Valentina Mancini," a researcher in UNIGE’s Department of Psychiatry. "And among people with deletion syndrome, the volume of the medial geniculate nucleus (the MGN, one of the sub-parts of the thalamus involved in the auditory pathways) and that of the other nuclei used in memory are smaller in the group with auditory hallucinations relative to the group that doesn’t experience any. The size of the MGN differs between the two groups from childhood with a divergent developmental trajectory.” 
The scientists made a further observation: in the patients suffering from auditory hallucinations, they noticed a hyper-connectivity between the thalamic nuclei and cortical areas devoted to the primary processing of hearing and Wernicke’s area, which is highly significant for understanding language. This type of thalamo-cortical hyper-connection is normal during childhood, when the neural networks are being formed. The fact that it persists during adolescence and then into adulthood is the sign that the connections have never reached maturity.