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May 14, 2021 Friday 02:58:27 PM IST

Hand Held Device to Detect Dengue

Science Innovations

Researchers at the Indian Institute of Technology, Delhi has developed a hand held device for early diagnosis of dengue virus. It is able to provide test results within one hour (rapid diagnosis). The Surface Enhanced Raman Spectroscopy (SERS) based platform has been successfully tested on the clinical blood samples collected from hundreds of individuals in collaboration with ICMR-National Institue of Malaria Research (NIMR), Delhi. A specialised technique called GLAD for synthesizing of nanosculptured thin films was used to fabricate silver nanorods array based SERS active biosensors in order to detect pathogens. Only 2 microlitres of a diluted serum was drop casted on the SERS substartes and Raman spectra were collected by flashing 785 nm laser beam through the device. All the data were fed in a statistical tool principal component analyzer (PCA) software. The integrated device was able to clearly differentiate the three sets of blood samples; dengue positive, negative and healthy.